Article
Familial scleroderma: nature, nurture or both?
Internal medicine journal - 1 Apr 2008
Englert H, Roberts-Thomson P J, Byth K, Manolios N
Abstract excerpt
BACKGROUND: The aim of the study was to investigate: (i) familial scleroderma (FS) risk factors, (ii) subtype concordance and (iii) relationship between dates (DSO) and ages (ASO) at scleroderma onset. METHODS: Forty-seven cases (23 families; 25 FS pairs) were identified. Scleroderma disease onset was defined by (i) Raynaud's onset, (ii) first symptom onset (1SxO), (iii) second symptom onset (2SxO) and (iv)...
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