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Article

Clinical, immunologic, and genetic features of familial systemic sclerosis.

Arthritis and rheumatism - 1 Jun 2007

Assassi Shervin, Arnett Frank C, Reveille John D, Gourh Pravitt, Mayes Maureen D

Abstract excerpt

OBJECTIVE: To examine whether the affected first-degree relatives within multicase systemic sclerosis (SSc; scleroderma) families are concordant for autoantibody profile, disease type, and HLA class II haplotypes and whether clinical expression and serologic characteristics of familial SSc differ from those of sporadic SSc. METHODS: Seven hundred ten SSc families from the Scleroderma Family Registry and DNA...

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Identifiers

PMID: 17530643
DOI: 10.1002/art.22647

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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