Article
Older age onset of systemic sclerosis - accelerated disease progression in all disease subsets.
Rheumatology (Oxford, England) - 1 Nov 2020
Moinzadeh Pia, Kuhr Kathrin, Siegert Elise, Mueller-Ladner Ulf, Riemekasten Gabriela, Günther Claudia, Kötter Ina, Henes Jörg, Blank Norbert, Zeidler Gabriele, Pfeiffer Christiane, Juche Aaron, Jandova Ilona, Ehrchen Jan, Schmalzing Marc, Susok Laura, Schmeiser Tim, Sunderkoetter Cord, Distler Jörg H W, Worm Margitta, Kreuter Alexander, Krieg Thomas, Hunzelmann Nicolas
Abstract excerpt
OBJECTIVES: Systemic sclerosis is a heterogeneous, multisystem disease. It can occur at any age, but most patients develop the disease between the age of 40 to 50 years. There is controversial evidence on whether/how the age at disease onset affects their clinical phenotype. We here investigate the relationship between age at disease onset and symptoms in a large cohort of SSc patients (lcSSc, dcSSc and...
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