Article
Viral load and its relationship to quinolinic acid, TNF alpha, and IL-6 levels in the CNS of retroviral infected mice.
Molecular and chemical neuropathology - 1 Aug 1994
Nagra R M, Heyes M P, Wiley C A
Abstract excerpt
Mouse models of infection of the central nervous system (CNS) have been used to study retroviral-induced neurologic disease. Ecotropic-neurotropic murine leukemia virus (MuLV) infection of susceptible neonatal mice causes a neurologic disease characterized by progressive hindlimb paralysis. The l...
Topics
- Animals
- Animals, Newborn
- Brain
- Brain Stem
- Female
- Interleukin-6
- Leukemia Virus, Murine
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C3H
- Moloney murine leukemia virus
- Mutation
- Nervous System Diseases
- Pregnancy
- Quinolinic Acid
- Retroviridae Infections
- Spinal Cord
- Tumor Necrosis Factor-alpha
