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Article

Expression and evolution of the non-canonically translated yeast mitochondrial acetyl-CoA carboxylase Hfa1p.

PloS one - 1 Jan 2014

Suomi Fumi, Menger Katja E, Monteuuis Geoffray, Naumann Uta, Kursu V A Samuli, Shvetsova Antonina, Kastaniotis Alexander J

Abstract excerpt

The Saccharomyces cerevisiae genome encodes two sequence related acetyl-CoA carboxylases, the cytosolic Acc1p and the mitochondrial Hfa1p, required for respiratory function. Several aspects of expression of the HFA1 gene and its evolutionary origin have remained unclear. Here, we determined the HFA1 transcription initiation sites by 5' RACE analysis. Using a novel "Stop codon scanning" approach, we mapped the...

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Identifiers

PMID: 25503745
DOI: 10.1371/journal.pone.0114738
PMCID: PMC4263661

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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