Chromosomal breakage in human spermatozoa, a heterozygous effect of the Bloom syndrome mutation.

Article

Chromosomal breakage in human spermatozoa, a heterozygous effect of the Bloom syndrome mutation.

American journal of human genetics - 1 Dec 1994

Martin R H, Rademaker A, German J

Abstract excerpt

The chromosome complements of 662 spermatozoa produced by the three fathers of individuals with Bloom syndrome (BS) were analyzed to determine whether the BS mutation could affect chromosome segregation and the frequency of aneuploidy in sperm. The frequency of numerical abnormalities was not sig...

Topics

Abnormalities, Multiple
Adult
Bloom Syndrome
Chromosome Aberrations
Chromosome Banding
Heterozygote
Humans
Karyotyping
Male
Meiosis
Mutation
Spermatozoa

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