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Analysis of DNA damage after human sperm cryopreservation in genes crucial for fertilization and early embryo development

22 Aug 2013

Abstract excerpt

Sperm cryopreservation is widely used in clinic for insemination, in vitro fertilization and other procedures such as intracytoplasmic sperm injection. The assessment after freezing/thawing of spermatozoa viability, motility and sometimes DNA integrity (mainly using fragmentation assays) has been considered enough to guarantee the safety and effectiveness of the technique. However, it is known that, even when...

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PMID: 23970451
DOI: 10.1111/j.2047-2927.2013.00116.x

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