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The effect of sperm DNA fragmentation on the incidence and origin of whole and segmental chromosomal aneuploidies in human embryos

30 May 2023

Abstract excerpt

In brief: Whether sperm DNA fragmentation (SDF) affects embryo development and clinical outcomes is still controversial, which limits the utility of SDF testing in assisted reproductive technology management. This study demonstrates that high SDF is associated with the incidence of segmental chromosomal aneuploidy and increased paternal whole chromosomal aneuploidies. Abstract: We aimed to investigate the...

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PMID: 37252832
DOI: 10.1530/rep-23-0011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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