Localization of disinhibition-dementia-parkinsonism-amyotrophy complex to 17q21-22.

Article

Localization of disinhibition-dementia-parkinsonism-amyotrophy complex to 17q21-22.

American journal of human genetics - 1 Dec 1994

Wilhelmsen K C, Lynch T, Pavlou E, Higgins M, Nygaard T G

Abstract excerpt

Disinhibition-dementia-parkinsonism-amyotrophy complex (DDPAC) is defined by familial adult-onset behavioral disturbance, followed by frontal lobe dementia, parkinsonism, and amyotrophy in variable proportions. A genetic etiology of DDPAC was suspected because of the familial clustering in family...

Topics

Chromosome Mapping
Chromosomes, Human, Pair 17
Dementia
Female
Genetic Markers
Genotype
Humans
Lod Score
Male
Muscular Diseases
Neuromuscular Diseases
Parkinson Disease
Pedigree

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