Article
Evidence, from family studies, for linkage disequilibrium between TGFA and a gene for nonsyndromic cleft lip with or without cleft palate.
American journal of human genetics - 1 Nov 1994
Feng H, Sassani R, Bartlett S P, Lee A, Hecht J T, Malcolm S, Winter R M, Vintiner G M, Buetow K H, Gasser D L
Abstract excerpt
The inheritance of alleles of the transforming growth factor alpha (TGFA) locus has been studied in families affected with cleft lip with or without cleft palate (CL/P), by using the transmission/disequilibrium test described by Spielman and colleagues. Only heterozygous parents with an affected...
Topics
- Alleles
- Cleft Lip
- Cleft Palate
- Female
- Humans
- Linkage Disequilibrium
- Male
- Pedigree
- Transforming Growth Factor alpha