Article
Evidence, from family studies, for linkage disequilibrium between TGFA and a gene for nonsyndromic cleft lip with or without cleft palate.
American journal of human genetics - 1 Nov 1994
Feng H, Sassani R, Bartlett S P, Lee A, Hecht J T, Malcolm S, Winter R M, Vintiner G M, Buetow K H, Gasser D L
Abstract excerpt
The inheritance of alleles of the transforming growth factor alpha (TGFA) locus has been studied in families affected with cleft lip with or without cleft palate (CL/P), by using the transmission/disequilibrium test described by Spielman and colleagues. Only heterozygous parents with an affected child can be included in this test, but within such families a significantly greater frequency of C2 alleles were...
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