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Article

Transforming growth factor alpha: a modifying locus for nonsyndromic cleft lip with or without cleft palate?

European journal of human genetics : EJHG - 1 Jan 1994

Field L L, Ray A K, Marazita M L

Abstract excerpt

Most (but not all) studies have found weak but significant association between restriction fragment length polymorphisms at the transforming growth factor alpha (TGFA) locus on chromosome 2p13 and nonsyndromic cleft lip with or without cleft palate (CL +/- P). However, all attempts to demonstrate genetic linkage between TGFA and CL +/- P in families have produced consistently negative lod scores which provide...

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Source

Identifiers

PMID: 7834275
DOI: 10.1159/000472359

Genes

TGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transforming growth factor alpha: a modifying locus for nonsyndromic cleft lip with or without cleft palate?PMID 7834275Read ↗

Transforming growth factor alpha locus and nonsyndromic cleft lip with or without cleft palate: a reappraisal.Semantic proximity Read ↗

Transforming Growth Factor Alpha Taq I Polymorphisms and Nonsyndromic Cleft Lip and/or Palate Risk: A Meta-Analysis.Semantic proximity Read ↗

Genetic effect of transforming growth factor alpha gene variants on the risk of nonsyndromic cleft lip with or without palate in korean populations.Semantic proximity Read ↗

Cleft lip and palate: no evidence of linkage to transforming growth factor alpha.Semantic proximity Read ↗

Evidence, from family studies, for linkage disequilibrium between TGFA and a gene for nonsyndromic cleft lip with or without cleft palate.Semantic proximity Read ↗

Association between alleles of the transforming growth factor alpha locus and cleft lip and palate in the Chilean population.Semantic proximity Read ↗

Association between the transforming growth factor alpha gene and nonsyndromic oral clefts: a HuGE review.Semantic proximity Read ↗

Transforming growth factor-beta receptor type 1 (TGFBR1) is not associated with non-syndromic cleft lip with or without cleft palate in patients of Central European descent.Semantic proximity Read ↗

Evidence for an association between nonsyndromic cleft lip with or without cleft palate and a gene located on the long arm of chromosome 4.Semantic proximity Read ↗

Oral clefts, transforming growth factor alpha gene variants, and maternal smoking: a population-based case-control study in Denmark, 1991-1994.Semantic proximity Read ↗

Genome scan for loci involved in nonsyndromic cleft lip with or without cleft palate in families from West Bengal, India.Semantic proximity Read ↗

TGFA/TAQ I polymorphism in nonsyndromic cleft lip and palate patients from Rio Grande Do Sul, Brazil.Semantic proximity Read ↗

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