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Article

Cleft lip and palate: no evidence of linkage to transforming growth factor alpha.

American journal of human genetics - 1 Sept 1991

Hecht J T, Wang Y P, Blanton S H, Michels V V, Daiger S P

Abstract excerpt

Recently, an association of a specific transforming growth factor alpha (TGFA) haplotype has been reported to occur in patients with nonsyndromic cleft lip and palate (CLP) who had a positive family history of the disorder. We tested linkage of CLP to TGFA in 12 multiplex families with clefting. TGFA haplotypes were constructed on the basis of three polymorphic restriction sites. No haplotype was associated with...

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Source

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Identifiers

PMID: 1679292
PMCID: PMC1683150

Genes

TGFA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Cleft lip and palate: no evidence of linkage to transforming growth factor alpha.PMID 1679292Read ↗

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Evidence, from family studies, for linkage disequilibrium between TGFA and a gene for nonsyndromic cleft lip with or without cleft palate.Semantic proximity Read ↗

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Association of MSX1 and TGFB3 with nonsyndromic clefting in humans.Semantic proximity Read ↗

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