Article
Cleft lip and palate: no evidence of linkage to transforming growth factor alpha.
American journal of human genetics - 1 Sept 1991
Hecht J T, Wang Y P, Blanton S H, Michels V V, Daiger S P
Abstract excerpt
Recently, an association of a specific transforming growth factor alpha (TGFA) haplotype has been reported to occur in patients with nonsyndromic cleft lip and palate (CLP) who had a positive family history of the disorder. We tested linkage of CLP to TGFA in 12 multiplex families with clefting....
Topics
- Alleles
- Cleft Lip
- Cleft Palate
- Female
- Genetic Linkage
- Genotype
- Humans
- Male
- Pedigree
- Polymorphism, Restriction Fragment Length
- Transforming Growth Factor alpha