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Article

Antimitotic and Cytotoxic Flavonols from Zieridium pseudobtusifolium and Acronychia porteri

1 Jul 1994

Abstract excerpt

Bioassay-guided fractionation of the extracts of Zieridium pseudobtusifolium and Acronychia porteri led to the isolation of 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone [1], which showed activity against (KB) human nasopharyngeal carcinoma cells (IC50 0.04 micrograms/ml) and inhibited tubulin assembly into microtubules (IC50 12 microM). Two other known flavonols, digicitrin [2] and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 7964782
DOI: 10.1021/np50109a024

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