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Article

A Grand Challenge. 3. Unbiased Phenotypic Function of Metabolites from Australia Plants Gloriosa superba and Alangium villosum against Parkinson's Disease.

Journal of natural products - 22 May 2020

Wang Dongdong, Murtaza Mariyam, Wood Stephen A, Mellick George D, Miao William Gang, Guymer Gordon P, Forster Paul I, Feng Yunjiang, Quinn Ronald J

Abstract excerpt

As part of a continuing research program aiming to identify chemical probes to interrogate Parkinson's disease (PD), we have investigated the Australian plants Gloriosa superba and Alangium villosum. The chemical investigations of G. superba resulted in the isolation of four new alkaloids, β-lumicolchicosides A-C (1-3) and γ-lumicolchicoside A (4), together with four lumicolchicine derivatives (5-8) and six...

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PMID: 32372642
DOI: 10.1021/acs.jnatprod.9b00880

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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