Article
Expression and functional activity of fibroblast growth factors and their receptors in human pancreatic cancer.
International journal of cancer - 1 Dec 1994
Leung H Y, Gullick W J, Lemoine N R
Abstract excerpt
We have analysed expression of the first 7 members of the family of heparin-binding fibroblast growth factor (FGFs) and their 4 high-affinity receptors (FGFRs) in human pancreatic carcinoma cell lines, both at the mRNA and protein levels. In cell lines expressing FGFRs, 2 typical patterns were observed: (i) expression of FGFR-I, -3 or -4 along with the expression of at least one FGF; (ii) co-expression of FGFR-3...
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