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Article

Fibroblast growth factor receptor 1 gene amplification in pancreatic ductal adenocarcinoma.

Histopathology - 1 Aug 2013

Lehnen Nils C, von Mässenhausen Anne, Kalthoff Holger, Zhou Hui, Glowka Tim, Schütte Ute, Höller Tobias, Riesner Katarina, Boehm Diana, Merkelbach-Bruse Sabine, Kirfel Jutta, Perner Sven, Gütgemann Ines

Abstract excerpt

AIMS: Pancreatic ductal adenocarcinomas (PDACs) are chemoresistant, resulting in extremely poor survival of patients; therefore, novel molecular targets, even in small subsets of genetically characterized tumours, are urgently needed. Tyrosine kinase receptor inhibitors (TKIs) are already in clinical use. The aims of this study were to examine the gene copy number and expression of fibroblast growth factor...

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Share to Carcinoma, Pancreatic Ductal
Share to Gene Amplification

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Hybridization, Fluorescence

Share to Pancreatic Neoplasms

Share to ras Proteins

Share to Receptor, Fibroblast Growth Factor, Type 1

Share to RNA, Neoplasm

Share to Tissue Array Analysis

Source

Identifiers

PMID: 23808822
DOI: 10.1111/his.12115

Genes

FGFR1
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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