Article
Bone morphogenetic protein -4 and -5 in pancreatic cancer--novel bidirectional players.
Experimental cell research - 10 Sept 2011
Virtanen Siru, Alarmo Emma-Leena, Sandström Saana, Ampuja Minna, Kallioniemi Anne
Abstract excerpt
Bone morphogenetic proteins (BMPs) are multifunctional signaling molecules that have gained increasing interest in cancer research. To obtain a systematic view on BMP signaling in pancreatic cancer we first determined the mRNA expression levels of seven BMP ligands (BMP2-BMP8) and six BMP specific receptors in pancreatic cancer cell lines and normal pancreatic tissue. BMP receptor expression was seen in all...
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