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Article

FGF10/FGFR2 signal induces cell migration and invasion in pancreatic cancer

1 Jul 2008

Abstract excerpt

Pancreatic cancer has one of the highest mortalities among all malignancies and there is an urgent need for new therapy. This might be achieved by resolving the detailed biological mechanism, and in this study we examined how pancreatic cancer cells develop aggressive properties by focusing on signalling through the fibroblast growth factor (FGF)10 and FGF receptor (FGFR)2, which play important roles in...

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PMID: 18594526
DOI: 10.1038/sj.bjc.6604473

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