Article
Homotypic and heterotypic protein associations control Rad51 function in double-strand break repair.
Genes & development - 1 Nov 1994
Donovan J W, Milne G T, Weaver D T
Abstract excerpt
Rad51 is essential for efficient repair of DNA double-strand breaks (DSBs) and recombination in Saccharomyces cerevisiae. Here, we examine Rad51 protein-protein interactions and their biological significance. GAL4 two-hybrid fusion analysis demonstrated that the amino-terminal region of Rad51 med...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- DNA Primers
- DNA Repair
- DNA-Binding Proteins
- Fungal Proteins
- Genes, Fungal
- Kinetics
- Kluyveromyces
- Molecular Sequence Data
- Phenotype
- Polymerase Chain Reaction
- Protein Multimerization
- Rad51 Recombinase
- Recombinant Fusion Proteins
- Saccharomyces cerevisiae