Article
[Genotoxic effects of pesticide fipronil in somatic and generative cells of mice].
Genetika - 1 May 2016
Lovinskaya A V, Kolumbayeva S Zh, Kolomiets O L, Abilev S K
Abstract excerpt
The pronounced genotoxic effect of fipronil in all used doses (4.75, 9.50, 19.00, and 31.70 mg/kg) at a single exposure in the liver, lungs and spleen was ascertained by the Comet assay. Organ specificity of genotoxic effects of the pesticide was revealed. The liver was the most sensitive to fipronil. Fipronil at a dose of 9.50 mg/kg in a single and repeated exposure (within 10 days) induced aberrations in mouse...
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