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Advancements and challenges in generating accurate animal models of gestational diabetes mellitus

2 Oct 2013

Abstract excerpt

The maintenance of glucose homeostasis during pregnancy is critical to the health and well-being of both the mother and the developing fetus. Strikingly, approximately 7% of human pregnancies are characterized by insufficient insulin production or signaling, resulting in gestational diabetes mellitus (GDM). In addition to the acute health concerns of hyperglycemia, women diagnosed with GDM during pregnancy have...

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PMID: 24085033
DOI: 10.1152/ajpendo.00425.2013

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