Article
Transgenic mice lacking white fat: models for understanding human lipoatrophic diabetes.
Annals of the New York Academy of Sciences - 18 Nov 1999
Reitman M L, Mason M M, Moitra J, Gavrilova O, Marcus-Samuels B, Eckhaus M, Vinson C
Abstract excerpt
The human disease lipoatrophic (or lipodystrophic) diabetes is a rare syndrome in which a deficiency of adipose tissue is associated with Type 2 diabetes. This disease is an interesting contrast to the usual situation in which diabetes is associated with obesity, an excess of fat. Aside from obesity, patients with lipodystrophic diabetes have the other features associated with Metabolic Syndrome X, including...
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