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Article

The Staphylococcus aureus mutation pcrA3 leads to the accumulation of pT181 replication initiation complexes.

Journal of molecular biology - 20 Oct 1991

Iordanescu S, Basheer R

Abstract excerpt

In Staphylococcus aureus cells carrying the pcrA3 chromosomal mutation, plasmid pT181 and its derivatives were maintained at a reduced copy number. A significant proportion of their DNA migrated during agarose gel electrophoresis as nicked DNA. The results obtained in the characterization of this plasmid DNA species show that it represents replication initiation complexes. Such complexes could not be detected in...

Topics

Bacterial Proteins
Blotting, Western
DNA Replication
Electrophoresis, Agar Gel
Kinetics
Mutation
Plasmids
Staphylococcus aureus

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1942047
DOI: 10.1016/0022-2836(91)90927-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1942047-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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The Staphylococcus aureus mutation pcrA3 leads to the accumulation of pT181 replication initiation complexes.PMID 1942047Read ↗

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