Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutational and physiological analyses of plasmid pT181 functions expressing incompatibility.

Plasmid - 1 Jan 1990

Highlander S K, Novick R P

Abstract excerpt

Plasmid pT181 is a small multicopy plasmid from Staphylococcus aureus that belongs to incompatibility group 3 and expresses two distinct types of incompatibility, Inc3A and Inc3B. Inc3A incompatibility is expressed by the primary replication control determinant, copA, which specifies two small transcripts, RNA I and RNA II, that jointly inhibit the synthesis of the rate-limiting initiator protein, RepC. Inc3B...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Proteins
Share to Base Sequence
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Replication

Share to Molecular Sequence Data

Share to Mutation

Share to Plasmids

Share to Repressor Proteins

Source

Identifiers

PMID: 1693440
DOI: 10.1016/0147-619x(90)90039-f

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational and physiological analyses of plasmid pT181 functions expressing incompatibility.PMID 1693440Read ↗

Replication-specific conversion of the Staphylococcus aureus pT181 initiator protein from an active homodimer to an inactive heterodimer.Semantic proximity Read ↗

The Staphylococcus aureus mutation pcrA3 leads to the accumulation of pT181 replication initiation complexes.Semantic proximity Read ↗

The PcrA3 mutant binds DNA and interacts with the RepC initiator protein of plasmid pT181 but is defective in its DNA helicase and unwinding activities.Semantic proximity Read ↗

In vitro studies of the initiation of staphylococcal plasmid replication. Specificity of RepD for its origin (oriD) and characterization of the Rep-ori tyrosyl ester intermediate.Semantic proximity Read ↗

Identification of a low-copy-number mutation within the pUB110 replicon and its effect on plasmid stability in Bacillus subtilis.Semantic proximity Read ↗

An rpsL-based allelic exchange vector for Staphylococcus aureus.Semantic proximity Read ↗

Characterization of the Staphylococcus aureus chromosomal gene pcrA, identified by mutations affecting plasmid pT181 replication.Semantic proximity Read ↗

Analysis of the pSK1 replicon, a prototype from the staphylococcal multiresistance plasmid family.Semantic proximity Read ↗

Comparative biology of two natural variants of the IncQ-2 family plasmids, pRAS3.1 and pRAS3.2.Semantic proximity Read ↗

General organization of the conjugal transfer genes of the IncW plasmid R388 and interactions between R388 and IncN and IncP plasmids.Semantic proximity Read ↗

A model for the evolution of biological specificity: a cross-reacting DNA-binding protein causes plasmid incompatibility.Semantic proximity Read ↗

Replication mutants of Staphylococcus aureus macrolide-lincosamide-streptogramin B resistance plasmid pT48.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.