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Article

Programmed cell death is affected in the novel mouse mutant Fused toes (Ft).

Development (Cambridge, England) - 1 Sept 1994

van der Hoeven F, Schimmang T, Volkmann A, Mattei M G, Kyewski B, Rüther U

Abstract excerpt

We have identified a novel dominant mouse mutant that is characterised by fused toes on the fore limbs and a thymic hyperplasia, in heterozygous animals. Homozygosity of the mutation leads to malformation of the developing brain, lost of the genetic control of left-right asymmetry and to death around day 10 of development. Analysis of both limb development and induction of apoptosis in immature thymocytes in...

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Identifiers

PMID: 7956835
DOI: 10.1242/dev.120.9.2601

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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