Article
The Caenorhabditis elegans gene lin-26 is required to specify the fates of hypodermal cells and encodes a presumptive zinc-finger transcription factor.
Development (Cambridge, England) - 1 Sept 1994
Labouesse M, Sookhareea S, Horvitz H R
Abstract excerpt
The mutation lin-26(n156) prevents vulva formation in C. elegans by transforming the vulval precursor cells into neurons or neuroblasts. We have isolated and characterized three new lin-26 alleles, which result in embryonic lethality. These mutations cause a few other hypodermal cells to express...
Topics
- Alleles
- Amino Acid Sequence
- Animals
- Base Sequence
- Blotting, Northern
- Caenorhabditis elegans
- Caenorhabditis elegans Proteins
- Cell Differentiation
- DNA-Binding Proteins
- Female
- Genes, Helminth
- Male
- Molecular Sequence Data
- Mutation
- Sequence Analysis, DNA
- Skin
- Transcription Factors
- Zinc Fingers