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Article

The Caenorhabditis elegans gene lin-26 can trigger epithelial differentiation without conferring tissue specificity.

Developmental biology - 15 Jul 2001

Quintin S, Michaux G, McMahon L, Gansmuller A, Labouesse M

Abstract excerpt

How epithelial cell fates become specified is poorly understood. We have previously shown that the putative C2H2 zinc-finger transcription factor LIN-26 is required for the differentiation of ectodermal and mesodermal epithelial cells in Caenorhabditis elegans. Here, we report that ectopic LIN-26 expression during early gastrulation transforms most blastomeres into epithelial-like cells. Specifically, LIN-26...

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Identifiers

PMID: 11437447
DOI: 10.1006/dbio.2001.0294

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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The Caenorhabditis elegans gene lin-26 can trigger epithelial differentiation without conferring tissue specificity.PMID 11437447Read ↗

The Caenorhabditis elegans LIN-26 protein is required to specify and/or maintain all non-neuronal ectodermal cell fates.Semantic proximity Read ↗

The zinc finger protein DIE-1 is required for late events during epithelial cell rearrangement in C. elegans.Semantic proximity Read ↗

The Caenorhabditis elegans gene lin-26 is required to specify the fates of hypodermal cells and encodes a presumptive zinc-finger transcription factor.Semantic proximity Read ↗

Multiple regulatory elements with spatially and temporally distinct activities control the expression of the epithelial differentiation gene lin-26 in C. elegansSemantic proximity Read ↗

A deficiency screen for zygotic loci required for establishment and patterning of the epidermis in Caenorhabditis elegans.Semantic proximity Read ↗

Nuclear receptor NHR-25 is required for cell-shape dynamics during epidermal differentiation in Caenorhabditis elegans.Semantic proximity Read ↗

The Caenorhabditis elegans heterochronic gene lin-29 coordinates the vulval-uterine-epidermal connections.Semantic proximity Read ↗

Game of Tissues: How the Epidermis Thrones C. elegans ShapeSemantic proximity Read ↗

Epithelial Shaping by Diverse Apical Extracellular Matrices Requires the Nidogen Domain Protein DEX-1 in Caenorhabditis elegansSemantic proximity Read ↗

CHE-14, a protein with a sterol-sensing domain, is required for apical sorting in C. elegans ectodermal epithelial cells.Semantic proximity Read ↗

The terminal differentiation factor LIN-29 is required for proper vulval morphogenesis and egg laying in Caenorhabditis elegans.Semantic proximity Read ↗

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