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Article

Molecular genetic methods for mapping disease genes.

American journal of respiratory and critical care medicine - 1 Nov 1994

Levitt R C

Abstract excerpt

Recent technological enhancements in molecular genetics have significantly improved our ability to locate disease genes by linkage analysis. Despite the introduction of molecular methods such as PCR and the discovery of highly polymorphic SSRs, genotyping is still rate-limiting for localizing disease genes by linkage. These methods have been, until recently, highly technical, time-consuming, and expensive. The...

Topics

Asthma
Base Sequence
Chromosome Mapping
Fluorescence
Genetic Linkage
Genetic Markers
Genetic Techniques
Genotype
Humans
Molecular Sequence Data
Phenotype

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PMID: 7952603
DOI: 10.1164/ajrccm/150.5_Pt_2.S94

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7952603-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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