Article
Association mapping: critical considerations shift from genotyping to experimental design.
The Plant cell - 1 Aug 2009
Myles Sean, Peiffer Jason, Brown Patrick J, Ersoz Elhan S, Zhang Zhiwu, Costich Denise E, Buckler Edward S
Abstract excerpt
The goal of many plant scientists' research is to explain natural phenotypic variation in terms of simple changes in DNA sequence. Traditionally, linkage mapping has been the most commonly employed method to reach this goal: experimental crosses are made to generate a family with known relatedness, and attempts are made to identify cosegregation of genetic markers and phenotypes within this family. In vertebrate...
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