Article
Origin of human mast cells: development from transplanted hematopoietic stem cells after allogeneic bone marrow transplantation.
Blood - 1 Nov 1994
Födinger M, Fritsch G, Winkler K, Emminger W, Mitterbauer G, Gadner H, Valent P, Mannhalter C
Abstract excerpt
Although mast cells are hematopoietic cells, little is known about the origin of their precursors in vivo. In this study, the origin (donor v recipient genotype) of human mast cells (MCs) was analyzed in a patient who underwent allogeneic bone marrow transplantation (BMT). The patient presented with secondary acute myeloid leukemia (French-American-British classification, M2) arising from refractory anemia with...
Topics
- Bone Marrow Transplantation
- Child
- Female
- Genotype
- Hematopoietic Stem Cells
- Humans
- Leukemia, Myeloid, Acute
- Lymphocyte Subsets
- Mast Cells
- Minisatellite Repeats
- von Willebrand Factor
