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Article

The origin of neoplastic mast cells in systemic mastocytosis with AML1/ETO-positive acute myeloid leukemia.

Experimental hematology - 1 Nov 2007

Nagai Sumimasa, Ichikawa Motoshi, Takahashi Tsuyoshi, Sato Hiroyuki, Yokota Hiromitsu, Oshima Kumi, Izutsu Koji, Hangaishi Akira, Kanda Yoshinobu, Motokura Toru, Chiba Shigeru, Yatomi Yutaka, Kurokawa Mineo

Abstract excerpt

OBJECTIVE: Systemic mastocytosis with associated clonal hematological non-mast cell lineage disease (SM-AHNMD) is a distinct entity that was defined by World Health Organization. Systemic mastocytosis with acute myeloid leukemia (AML) is frequently seen among SM-AHNMD. However, the pathogenesis or origin of neoplastic mast cells has not been fully elucidated in this category of diseases. METHODS: We examined KIT...

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Share to Antigens, CD34
Share to Core Binding Factor Alpha 2 Subunit

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Mastocytosis, Systemic

Share to Oncogene Proteins, Fusion

Share to Proto-Oncogene Proteins c-kit

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Source

Identifiers

PMID: 17976525
DOI: 10.1016/j.exphem.2007.08.016

Genes

KIT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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