Article
Blood CD34-c-Kit+ cell rate correlates with aggressive forms of systemic mastocytosis and behaves like a mast cell precursor.
Blood - 10 Nov 2011
Georgin-Lavialle Sophie, Lhermitte Ludovic, Baude Cédric, Barete Stéphane, Bruneau Julie, Launay Jean-Marie, Chandesris Marie-Olivia, Hanssens Katia, de Gennes Christian, Damaj Gandhi, Lanternier Fanny, Hamidou Mohamed, Lortholary Olivier, Dubreuil Patrice, Feger Frédéric, Lepelletier Yves, Hermine Olivier
Abstract excerpt
Mastocytosis is a heterogeneous disease characterized by the accumulation of mast cells in one or more organs. Our objective was to identify a peripheral mast cell precursor and assess its variation rate in mastocytosis. A peripheral blood phenotypic analysis was performed among 50 patients with mastocytosis who were enrolled in a prospective multicentric French study, and the phenotypic analysis results of the...
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