Article
Immune recognition, antigen design, and catalytic antibody production.
Applied biochemistry and biotechnology - 1 Jan 2000
Tramontano A
Abstract excerpt
Catalytic antibodies have been developed by experimental approaches exploiting the analogy between antibody-antigen and enzyme-substrate interaction. Haptens have been prepared to model the electrostatic or geometric attributes of a reaction's transition state and to induce combining sites having...
Topics
- Antibodies, Catalytic
- Antigen-Antibody Complex
- Catalysis
- Chromatography, Affinity
- Haptens
- Humans
- Models, Molecular
- Mutation
- Structure-Activity Relationship
- Substrate Specificity