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Antibody therapeutics:

29 Aug 2007

Abstract excerpt

Recombinant monoclonal antibody (rMAb) therapy may be instituted to achieve one of two broad outcomes: i) killing of cells or organisms (e.g., cancer cells, bacteria); and ii) neutralisation of soluble molecules (e.g., cytokines in chronic disease or toxins in infection). The choice of rMAb isotype is a critical decision in the development of a therapeutic antibody as it will determine the biological activities...

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Identifiers

PMID: 17727329
DOI: 10.1517/14712598.7.9.1401

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