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Article

The Reed-Sternberg cells of Hodgkin disease are clonal.

Proceedings of the National Academy of Sciences of the United States of America - 11 Oct 1994

Inghirami G, Macri L, Rosati S, Zhu B Y, Yee H T, Knowles D M

Abstract excerpt

Relatively little progress has been made in understanding the nature of the Reed-Sternberg (RS) cell and its morphologic variants in Hodgkin disease (HD). This is primarily due to the fact that RS cells represent a minute subpopulation within HD lesions. To investigate the clonal origin of RS cells and variants, we studied 27 HD lesions obtained from 11 patients. Using an image analyzer (CAS 200) we were able to...

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Identifiers

PMID: 7937902
DOI: 10.1073/pnas.91.21.9842
PMCID: PMC44913

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The Reed-Sternberg cells of Hodgkin disease are clonal.PMID 7937902Read ↗

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