Advances in biology, diagnostics, and treatment of Hodgkin's disease.

Abstract excerpt

Hodgkin and Reed-Sternberg cells are derived from germinal center B cells. Amplification of identical rearranged and mutated immunoglobulin genes from different Hodgkin and Reed-Sternberg cells from the same patient also answered the question of the malignant nature because the clonality-the key criterion of malignancy-of Hodgkin and Reed-Sternberg cells was hereby shown. In addition, it could be demonstrated...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Combined Modality Therapy
• Share to Disease-Free Survival