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Article

Molecular analysis of Hodgkin's disease with abundant Reed-Sternberg cells.

Hematologic pathology - 1 Jan 1990

Hu E H, Ellison D, Zovich D, Nichols P, Pattengale P

Abstract excerpt

The pathogenesis of Hodgkin's disease (HD) has been elusive largely because of the paucity of the Reed-Sternberg cells in comparison to large numbers of normal inflammatory cells in biopsy specimens. This report attempts to characterize Hodgkin's disease by studying subtypes with a high proportion of Reed-Sternberg cells and their variants. We found in 4 out of 6 cases, clonal heavy and light chain immunoglobulin...

Topics

Cell Count
Cloning, Molecular
Gene Rearrangement
Hodgkin Disease
Humans
Phenotype

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2341365

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2341365-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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