Article
Localization of the gene for Darier disease to a 5-cM interval on chromosome 12q.
The Journal of investigative dermatology - 1 Oct 1994
Ikeda S, Wakem P, Haake A, Ewing N, Polakowska R, Sarret Y, Trattner A, David M, Shohat M, Schroeder D W
Abstract excerpt
Darier disease is an autosomal dominant abnormality of epidermal differentiation characterized clinically by the presence of hyperkeratotic papules on the skin and histologically by the loss of cell cohesion and by disorderly keratinization. Two groups recently found evidence that the gene whose mutations underlie this disease is located at chromosome 12q23-q24.1, a site on chromosome 12 that clearly is distal to...
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