Article
Hailey-Hailey disease is not allelic to Darier's disease.
The Journal of investigative dermatology - 1 Jun 1994
Welsh E A, Ikeda S, Peluso A M, Bonifas J M, Bare J W, Woodley D T, Epstein E H
Abstract excerpt
Hailey-Hailey (Familial Benign Chronic Pemphigus) Disease is a rare autosomal dominant disorder characterized by blisters caused by suprabasal epidermal acantholysis. Another autosomal dominant skin disease, Darier's disease, has clinical and histologic features which overlap those of Hailey-Hailey disease and recently has been mapped to chromosome 12q23-q24.1. We have used linkage analysis to test whether or not...
Topics
- Adolescent
- Adult
- Alleles
- Carrier Proteins
- Chromosome Mapping
- Chromosomes, Human, Pair 12
- Cytoskeletal Proteins
- Darier Disease
- Desmoplakins
- Family Health
- Female