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Article

Dictyostelium RacH regulates endocytic vesicular trafficking and is required for localization of vacuolin.

Traffic (Copenhagen, Denmark) - 1 Sept 2006

Somesh Baggavalli P, Neffgen Carola, Iijima Miho, Devreotes Peter, Rivero Francisco

Abstract excerpt

Dictyostelium RacH localizes predominantly to membranes of the nuclear envelope, endoplasmic reticulum and Golgi apparatus. To investigate the role of this protein, we generated knockout and overexpressor strains. RacH-deficient cells displayed 50% reduced fluid-phase uptake and a moderate exocytosis defect, but phagocytosis was unaffected. Detailed examination of the endocytic pathway revealed defective...

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Identifiers

PMID: 17004322
DOI: 10.1111/j.1600-0854.2006.00455.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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