A putative two-component regulatory system involved in secondary metabolism in Streptomyces spp.

doi:10.1128/jb.174.23.7585-7594.1992

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Article

A putative two-component regulatory system involved in secondary metabolism in Streptomyces spp.

Journal of bacteriology - 1 Dec 1992

Ishizuka H, Horinouchi S, Kieser H M, Hopwood D A, Beppu T

Abstract excerpt

A DNA fragment stimulating actinorhodin, undecylprodigiosin, and A-factor production in Streptomyces lividans 66 was cloned from Streptomyces coelicolor A3(2). Nucleotide sequencing revealed the presence of an open reading frame of 225 codons, named afsQ1, that showed great similarity in amino acid sequence to the response regulators of typical prokaryotic two-component regulatory systems responsible for adaptive...

Topics

4-Butyrolactone
Actinomycetales
Amino Acid Sequence
Anthraquinones
Bacterial Proteins
Base Sequence
Chromosome Mapping
Cloning, Molecular
Gene Expression Regulation, Bacterial
Genes, Bacterial
Genes, Suppressor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Growth Substances

Histidine Kinase

Molecular Sequence Data

Mutagenesis, Site-Directed

Phenotype

Prodigiosin

Protein Kinases

Source

Open in PubMed Open full text

Identifiers

PMID: 1339426
DOI: 10.1128/jb.174.23.7585-7594.1992
PMCID: PMC207469

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1339426-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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A putative two-component regulatory system involved in secondary metabolism in Streptomyces spp.PMID 1339426Read ↗

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