An Escherichia coli K-12 tktA tktB mutant deficient in transketolase activity requires pyridoxine (vitamin B6) as well as the aromatic amino acids and vitamins for growth.

Abstract excerpt

We show that a tktA tktB double mutant, which is devoid of the two known transketolase isoenzymes of Escherichia coli K-12, requires pyridoxine (vitamin B6) as well as the aromatic amino acids and vitamins for growth. This pyridoxine requirement can also be satisfied by 4-hydroxy-L-threonine or g...

Topics

• Amino Acids
• Escherichia coli
• Genes, Bacterial
• Isoenzymes
• Mutation
• Pyridoxine
• Transketolase
• Vitamins