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Article

The PduX enzyme of Salmonella enterica is an L-threonine kinase used for coenzyme B12 synthesis.

The Journal of biological chemistry - 25 Apr 2008

Fan Chenguang, Bobik Thomas A

Abstract excerpt

Here, the PduX enzyme of Salmonella enterica is shown to be an L-threonine kinase used for the de novo synthesis of coenzyme B(12) and the assimilation of cobyric acid (Cby). PduX with a C-terminal His tag (PduX-His(6)) was produced at high levels in Escherichia coli, purified by nickel affinity chromatography, and partially characterized. (31)P NMR spectroscopy established that purified PduX-His(6) catalyzed the...

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Identifiers

PMID: 18308727
DOI: 10.1074/jbc.M800287200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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