Article
Bacterial resistance: origins, epidemiology, and impact.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Jan 2003
Livermore David M
Abstract excerpt
The basic mechanisms of antibacterial resistance are well known, but critical new aspects continue to be discovered. Recently discovered factors with major implications for the emergence, dissemination, and maintenance of resistance include multidrug efflux, hypermutability, integrons, and plasmid addiction. Some resistances are widespread and others local, with prevalence rates often worst in newly prosperous...
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