Article
Characterization and structural analysis of a functional human serum transferrin variant and implications for receptor recognition.
Biochemistry - 18 Oct 1994
Evans R W, Crawley J B, Garratt R C, Grossmann J G, Neu M, Aitken A, Patel K J, Meilak A, Wong C, Singh J
Abstract excerpt
The nucleotide and amino acid substitutions leading to the only known functional variant of human serum transferrin have been characterized by sequencing of a peptide produced by cyanogen bromide digestion and genomic PCR coupled with cycle sequencing, respectively. There is an amino acid substit...
Topics
- Aluminum
- Base Sequence
- Binding Sites
- Codon
- Copper
- Cyanogen Bromide
- Humans
- Models, Molecular
- Molecular Sequence Data
- Molecular Structure
- Mutation
- Polymerase Chain Reaction