Article
A comparison of the structure and properties of normal human transferrin and a genetic variant of human transferrin.
The International journal of biochemistry - 1 Jan 1990
Welch S, Langmead L
Abstract excerpt
1. A rare genetic variant of human serum transferrin (TfBSHAW) is reported. 2. The variant and normal transferrins have been purified. 3. The two proteins have been shown to be identical with respect to their molecular weights, heat stability, iron uptake and absorbance spectra. 4. The amino acid substitution is thought to be isoleucine replaced by asparagine at either position 378 or position 381. 5. The ferric...
Topics
- Amino Acids
- Chromatography, Gel
- Electrophoresis, Polyacrylamide Gel
- Ferric Compounds
- Hot Temperature
- Humans
- Hydrogen-Ion Concentration
- Molecular Weight
- Mutation
- Pedigree
- Protein Denaturation