Sloppy paired 1/2 regulate glial cell fates by inhibiting Gcm function.

Abstract excerpt

Organization of the central nervous system during embryonic development is an intricate process involving a host of molecular players. The Drosophila segmentation genes, sloppy paired (slp) 1/2 have been shown to be necessary for development of a neuronal precursor cell subtype, the NB4-2 cells. Here, we show that slp1/2 also have roles in regulating glial cell fates. Using slp1/2 loss-of-function mutants, we...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cell Lineage
• Share to Central Nervous System
• Share to Chlorocebus aethiops