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Article

Regulation of type 1 fimbriae synthesis and biofilm formation by the transcriptional regulator LrhA of Escherichia coli.

Microbiology (Reading, England) - 1 Oct 2005

Blumer Caroline, Kleefeld Alexandra, Lehnen Daniela, Heintz Margit, Dobrindt Ulrich, Nagy Gábor, Michaelis Kai, Emödy Levente, Polen Tino, Rachel Reinhard, Wendisch Volker F, Unden Gottfried

Abstract excerpt

Type 1 fimbriae of Escherichia coli facilitate attachment to the host mucosa and promote biofilm formation on abiotic surfaces. The transcriptional regulator LrhA, which is known as a repressor of flagellar, motility and chemotaxis genes, regulates biofilm formation and expression of type 1 fimbriae. Whole-genome expression profiling revealed that inactivation of lrhA results in an increased expression of...

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PMID: 16207912
DOI: 10.1099/mic.0.28098-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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