Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of MOR and the CI operator sites on the genetic switch of the temperate bacteriophage TP901-1.

Journal of molecular biology - 19 Dec 2008

Pedersen Margit, Hammer Karin

Abstract excerpt

A genetic switch controls whether the temperate bacteriophage TP901-1 will enter a lytic or a lysogenic life cycle after infection of its host, Lactococcus lactis. We studied this bistable switch encoded in a small DNA fragment of 979 bp by fusing it to a reporter gene on a low-copy-number plasmid. The cloned DNA fragment contained the two divergently oriented promoters, P(R) and P(L), transcribing the lysogenic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteriophage lambda
Share to Erythromycin
Share to Lactococcus lactis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lysogeny

Share to Plasmids

Share to Repressor Proteins

Share to Transcription, Genetic

Share to Viral Proteins

Source

Identifiers

PMID: 18930065
DOI: 10.1016/j.jmb.2008.09.071

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of MOR and the CI operator sites on the genetic switch of the temperate bacteriophage TP901-1.PMID 18930065Read ↗

Identification of quaternary structure and functional domains of the CI repressor from bacteriophage TP901-1.Semantic proximity Read ↗

Characterization of the genetic switch from phage ɸ13 important for Staphylococcus aureus colonization in humans.Semantic proximity Read ↗

The leucine-responsive regulatory protein binds to the fim switch to control phase variation of type 1 fimbrial expression in Escherichia coli K-12.Semantic proximity Read ↗

New Insights into the Phage Genetic Switch: Effects of Bacteriophage Lambda Operator Mutations on DNA Looping and Regulation of PR, PL, and PRM.Semantic proximity Read ↗

Octamerization of lambda CI repressor is needed for effective repression of P(RM) and efficient switching from lysogeny.Semantic proximity Read ↗

Characterization of the genetic switch from phage phi13 important for Staphylococcus aureus colonization in humansSemantic proximity Read ↗

Relatively slow stochastic gene-state switching in the presence of positive feedback significantly broadens the region of bimodality through stabilizing the uninduced phenotypic state.Semantic proximity Read ↗

Cooperative DNA binding by CI repressor is dispensable in a phage lambda variant.Semantic proximity Read ↗

Clear Plaque Mutants of Lactococcal Phage TP901-1.Semantic proximity Read ↗

Moonlighting bacteriophage proteins derepress staphylococcal pathogenicity islands.Semantic proximity Read ↗

Analysis of a regulator involved in the genetic switch between lysis and lysogeny of the temperate Lactococcus lactis phage phi LC3.Semantic proximity Read ↗

DNA looping provides stability and robustness to the bacteriophage lambda switch.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.