Article
Mismatch PCR RFLP detection of DRD2 Ser311Cys polymorphism and schizophrenia.
Biochemical and biophysical research communications - 29 Jul 1994
Hattori M, Nanko S, Dai X Y, Fukuda R, Kazamatsuri H
Abstract excerpt
We tested 100 schizophrenics and 100 controls to find association at the Serine311 Cysteine polymorphism of dopamine D2 receptor in Japanese population. There were no significant differences between the two groups. One homozygote for Cys311 was confirmed in the controls by mismatch-polymerase cha...
Topics
- Alleles
- Base Sequence
- Cysteine
- DNA
- Female
- Genotype
- Humans
- Japan
- Male
- Molecular Sequence Data
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Receptors, Dopamine D2
- Schizophrenia
- Serine
